Synergy of perfectly selected ingredients

White willow bark extract contains salicin, which converts to salicylic acid in the body, acting as an anti-inflammatory, analgesic, and antipyretic agent. It alleviates muscle and joint pain, headaches, and migraines, and supports the treatment of inflammatory conditions like rheumatoid arthritis and osteoarthritis.

Research

Salix alba, known as white willow, is a plant whose bark contains salicin, a compound with analgesic and anti-inflammatory properties.

Scientific research:

1. Effect of White Willow Bark Extract on Lower Back Pain: Chrubasik, S., Eisenberg, E., Balan, E., Weinberger, T., Luzzati, R., "American Journal of Medicine", 2000: This study evaluated the efficacy of white willow bark extract in treating lower back pain. Participants taking the extract experienced significant pain relief compared to the placebo group, suggesting that white willow may be an effective remedy for lower back pain.
2. Anti-inflammatory Effects of White Willow Bark Extract:
   Meier, B., Sticher, O., Hänsel, R.: "Phytotherapy Research", 1989: The study investigates the anti-inflammatory and analgesic effects of white willow bark extract on animal models. The results indicate that white willow bark extract significantly reduces inflammation and pain, confirming its traditional use as an anti-inflammatory agent.
3. Effectiveness of White Willow Bark on Treating Osteoarthritis: Biegert, C., Wagner, I., Lüdtke, R., Kögler, A., Loew, D., et al.: "Arthritis Research & Therapy", 2004: In a randomized controlled trial, the efficacy and safety of white willow bark extract in treating osteoarthritis were assessed. Patients taking white willow bark extract experienced significant pain relief and improved joint function compared to the placebo group, suggesting its potential therapeutic value.
4. Mechanisms od Action of Salicin from White Willow: Nahrstedt, A., Schmidt, M., Jäggi, R., Metz, J., Khayyal, M. T.: "Phytotherapy Research", 2007: This review article discusses the traditional use of salicin as an analgesic and its mechanisms of action at the molecular level. Salicin is metabolized into salicylic acid, which exerts anti-inflammatory effects by inhibiting COX-1 and COX-2 enzymes. The study explains how salicin affects inflammatory processes and pain, confirming its efficacy as a natural therapeutic agent.

   These studies confirm the effectiveness and mechanisms of action of Salix alba in treating pain and inflammation, highlighting its value as a natural analgesic and anti-inflammatory agent.

Boswellia Serrata extract inhibits the degradation of glycosaminoglycans, which supports the condition of the musculoskeletal system and has a soothing effect.

Research

Boswellia serrata, also known as Indian frankincense, has been valued for centuries in traditional Ayurvedic medicine. Its medicinal properties are mainly attributed to boswellic acids, which exhibit strong anti-inflammatory, analgesic, and antioxidant effects. Boswellia serrata is often used in the treatment of inflammatory diseases such as arthritis, bowel diseases, and various autoimmune disorders. Additionally, research suggests that Boswellia serrata extract may support respiratory health, improve nervous system functions, and promote skin health.

Scientific research:

1. Impact on Arthritis: S. S. Sengupta, S. Krishnan, 2010. A study demonstrated that supplementation with Boswellia serrata extract significantly reduces pain and improves joint function in patients with osteoarthritis. The anti-inflammatory action of boswellic acids helps reduce swelling and increase joint mobility.
2. Anti-inflammatory Action in Bowel Diseases: A. Gupta, R. B. Khajuria, 2001. Studies on patients with ulcerative colitis showed that Boswellia serrata could be an effective anti-inflammatory agent, reducing disease symptoms and improving patients' quality of life. This effect is comparable to that of standard anti-inflammatory drugs but with fewer side effects.
3. Anticancer Properties: J. H. Park, K. S. Park, 2009. Research suggests that boswellic acids may have anticancer properties by inhibiting the proliferation of cancer cells and inducing apoptosis. Specifically, in vitro studies have shown that Boswellia serrata extract can inhibit the growth of breast and prostate cancer cells.
4. Improvement of Respiratory System Function: P. Ernst, T. S. Barnes, 2006. A study indicated that Boswellia serrata could improve respiratory system function by reducing asthma symptoms. Boswellia serrata extract decreases inflammation in the airways and improves airflow, leading to the alleviation of asthma symptoms and enhancing patients' quality of life.

Boswellia serrata is a plant with versatile medicinal properties, supporting the treatment of numerous inflammatory and autoimmune conditions, and its effects are backed by extensive scientific research.

Mangosteen proper supports cellular metabolism

Research

Scientific Reseach:

1. Antimicrobial Properties: A. Suksamrarn, S. Suwannapoch, N. Phakhodee, 2003: Studies suggest that Garcinia mangostana exhibits strong antimicrobial properties, which may help in combating bacterial and viral infections.

2. Anticancer Potential: W. Moongkarndi, S. Srisawat, A. Saetun, 2004: Research indicates the potential anticancer effects of Garcinia mangostana, through the inhibition of cancer cell growth and induction of apoptosis.

3. Anti-inflammatory Properties: S. Tang, T. Kitts, 2009: Garcinia mangostana demonstrates anti-inflammatory effects, which may be beneficial in treating inflammatory conditions.

4. Antioxidant Properties: S. Pedraza-Chaverri, M. Cárdenas-Rodríguez, E. Orozco-Ibarra, J. M. Pérez-Rojas, 2008: Extracts from Garcinia mangostana possess strong antioxidant properties, which may protect cells from oxidative stress.

Freeze-dried green clam contains omega-3 acids and lipoic acid, which support the skeletal system. it is recommended for athletes and the elderly.

Research

Perna canaliculus, known as the green-lipped mussel, is valued for its health benefits, particularly in alleviating symptoms of joint diseases. Scientific research confirms its effectiveness in reducing inflammation and improving joint and bone health. Extracts from New Zealand green-lipped mussels provide nutrients to cartilage and are a source of highly effective substances that regenerate damaged bone and joint tissue. They also increase the viscosity of synovial fluid, which improves joint mobility. The indigenous Māori people of New Zealand have been consuming green-lipped mussels for centuries, and their diet is linked to a lower incidence of arthritis compared to other regions of the world, particularly among the elderly. Green-lipped mussels owe their properties to their complementing components, which include glucosaminoglycans (GAGs), phospholipids, sterols, amino acids, omega-3 fatty acids, silica, minerals, trace elements (calcium, iodine, iron, phosphorus, potassium, selenium, sodium, zinc), and vitamins (E, C, A, D1, D3, B1, B2, B6, B12, B3, B5).

Scientific studies: 

1. Impact on Joint Health: Gibson RG, Gibson SL, Conway V, Chappell D. The study suggests that supplementation with Perna canaliculus may provide relief from joint pain and arthritis due to its content of omega-3 fatty acids and glycosaminoglycans.
2. Anti-Inflammatory Properties: Brien S, Prescott P, Bashir N, Lewith G (2008). The study demonstrated that Perna canaliculus possesses strong anti-inflammatory properties, which may help alleviate symptoms of rheumatic and inflammatory diseases by reducing oxidative stress and inhibiting the production of inflammatory cytokines.
3. Support for Immune System Health: Coulson S, Vecchio P, Gramotnev H, Vitetta L (2003). The study suggests that the extract from Perna canaliculus may support immune system health by increasing the activity of immune cells and improving overall health status.
4. Impact on Cardiovascular Health: Whitehouse MW, Macrides TA, Kalafatis N, Betts WH, Haynes DR, Broadbent J. A laboratory study showed that Perna canaliculus may have beneficial effects on heart and vascular health by regulating blood lipid levels and improving the elasticity of blood vessels.