Synergy of perfectly selected ingredients

Marine collagen is a dietary supplement used to support the health of skin, joints, and bones. Its structure and composition are considered optimal for regenerating native collagen reserves.

Research

1. Impact of Marine Collagen on Skin Health: Proksch and colleagues conducted a clinical study in 2014 which showed that supplementation with marine collagen improves skin elasticity and reduces wrinkles. The study included a group of women over the age of 35 and revealed significant cosmetic benefits after 8 weeks of supplementation.

2. Impact of Marine Collagen on Joint Health: Moskowitz studied the effects of marine collagen on patients with osteoarthritis in 2000. The results suggested that collagen supplementation may reduce joint pain and improve joint function, which could be beneficial for individuals suffering from degenerative joint diseases.

3. Marine Collagen and Bone Health: Wu and colleagues conducted an animal study in 2004, which demonstrated that marine collagen could support bone mineralization and prevent bone mass loss. The study suggested that collagen might have potential applications in the prevention of osteoporosis.

4. Impact of Marine Collagen on Muscle Regeneration: Oesser and colleagues investigated the effects of marine collagen on muscle tissue regeneration after injuries in 1999. Their findings indicated that collagen supplementation accelerates muscle regeneration processes and improves muscle endurance, which is beneficial for athletes and physically active individuals.

Sodium hyaluronate works similarly to hyaluronic acid but has smaller molecules, allowing it to penetrate deeper into the skin.

Research

1. Treatment of Osteoarthritis: A study published in "Arthritis and Rheumatism" found that hyaluronic acid injections can significantly improve joint function and reduce pain in patients with osteoarthritis. Hyaluronic acid acts as a moisturizing and lubricating agent for the joints, making movement easier and reducing pain.

2. Effect on Skin Health: Research published in the "Journal of Clinical and Aesthetic Dermatology" demonstrated that the use of creams and serums containing hyaluronic acid improves skin hydration and reduces the appearance of wrinkles. Regular use of products with Sodium Hyaluronate contributes to improved skin elasticity and the reduction of signs of aging.

3. Eye Protection: In the "Journal of Ophthalmology", a study was described that examined the use of hyaluronic acid in the treatment of dry eye syndrome. Eye drops containing hyaluronic acid significantly improved hydration and comfort for patients with this condition.

4. Wound Healing: A study published in "Wound Repair and Regeneration" showed that applying hyaluronic acid gel to wounds accelerates the healing process and reduces the risk of infection. Sodium Hyaluronate supports tissue regeneration and has anti-inflammatory effects.

Zinc is an essential nutrient involved in numerous metabolic processes, including protein synthesis, immune system function, and gene expression. Zinc deficiency can lead to various disorders, such as diarrhea, weakened immune function, infections, cognitive impairments, and sperm damage in men.

Research

1. Impact of Zinc on Human Health: A study published in the "Archives of Toxicology" details the multifaceted impact of zinc on human health. Zinc is an essential nutrient involved in many metabolic processes, including protein synthesis, immune system function, and gene expression. Zinc deficiency can lead to numerous disorders, such as diarrhea, weakened immune function, infections, cognitive impairments, and sperm damage in men (SpringerLink).

2. Review of Zinc Intake and Health Outcomes: A systematic review published in "Frontiers in Nutrition" summarizes evidence on the relationship between zinc intake and various health outcomes. The study includes 43 articles, identifying 11 outcomes related to dietary zinc intake and 86 outcomes related to zinc supplementation. High dietary zinc intake may reduce the risk of various diseases, including respiratory infections and gastrointestinal issues (Frontiers).

3. Zinc Supplementation in Premature or Low Birth Weight Infants: A study published in "Pediatrics" evaluates the impact of zinc supplementation on the health of premature infants and those with low birth weight. The results indicate that zinc supplementation can improve growth, reduce mortality, and enhance neurological development in these children. The study highlights the importance of zinc in the diet of newborns for overall health and development (AAP Publications).

4. Anti-inflammatory and Immunomodulatory Properties of Zinc: A study published in the "Journal of Nutrition" explores the anti-inflammatory and immunomodulatory properties of zinc. Zinc plays a crucial role in regulating the immune response, and its deficiency can lead to weakened immunity and increased susceptibility to infections. The study suggests that appropriate zinc supplementation can enhance immune function and reduce inflammation in the body (SpringerLink).

Sunflower seeds (phospholipids from phosphatidylcholine) support cell structure, brain health, and liver function. Phosphatidylcholine is essential for maintaining healthy cell membranes, improves cognitive functions, and reduces liver damage.

Research

1. Liver Health Support: Studies have shown that phosphatidylcholine (PC) may protect the liver from damage, especially in cases of fatty liver disease. PC supports the regeneration of liver cells and reduces inflammation in the liver, which may be helpful in the treatment of conditions such as alcoholic fatty liver disease (MDPI)​ (Examine).

2. Improvement of Brain Function and Memory: Phosphatidylcholine plays a key role in brain health by supporting the synthesis of acetylcholine, a neurotransmitter responsible for memory and cognitive functions. Research has shown that PC supplementation can improve cognitive function, particularly in older adults, and may be used in the treatment of neurodegenerative diseases such as Alzheimer's disease (Linus Pauling Institute).

3. Reduction of Cholesterol Levels: Phosphatidylcholine supplementation helps lower LDL cholesterol levels, which has a beneficial effect on heart health and the circulatory system. Studies suggest that PC may support lipid metabolism, contributing to a reduced risk of atherosclerosis ​(MDPI) (Examine).

4. Support for Lipolysis: Phosphatidylcholine is also used in medical treatments for reducing body fat. The use of PC injections in areas of fat accumulation, such as the abdomen or thighs, has been shown to support the process of lipolysis, leading to a reduction in fat tissue (Examine).

Collagen is a structural protein that occurs naturally in the skin. Helps improve skin elasticity and reduce wrinkles.

Research

1. Collagen's Impact on Skin: A study found that collagen supplementation improves skin elasticity and hydration in women (PubMed).

2. Collagen and Joint Health: Type II collagen has been shown to reduce biomarkers of cartilage degradation in patients with knee osteoarthritis, leading to improved joint function (BMC).

3. Collagen and Bone Health: Research demonstrated that collagen hydrolysate improves bone mineral density in postmenopausal women with osteopenia or osteoporosis, potentially reducing the risk of fractures (Maturitas).

4. Collagen and Heart Health: A study suggests that collagen peptide supplementation may alleviate the atherosclerotic process and reduce vascular calcification, potentially benefiting cardiovascular health.

Bitter orange fruit extract contains vitamin P, which reduces the permeability of blood vessels and facilitates the absorption of vitamin C, and affects the proper functioning of the brain.

Research

Citrus aurantium, known as bitter orange, is a plant used for its potential health benefits. Extracts from this plant contain synephrine, which may aid in weight loss by increasing metabolism and reducing appetite. Additionally, bitter orange is used in dietary supplementation for its anti-inflammatory and antiviral effects.

1. Weight Loss and Metabolism Effects: Colker CM, Kalman DS, Torina GC, Perlis T, Street C, 1999. This study found that supplementation with Citrus aurantium extract may support weight loss by increasing metabolic rate and promoting fat oxidation in healthy adults.

2. Anti-inflammatory and Antioxidant Properties: Yamamoto M, Inoue S, Yoshikawa T, Nishiyama Y, 2011. The study determined that Citrus aurantium has strong anti-inflammatory and antioxidant properties, which can protect cells from damage caused by oxidative stress and reduce inflammation.

3. Cardiovascular Health: Stohs SJ, Preuss HG, Shara M, Kaats GR, 2012. Research suggests that Citrus aurantium may support cardiovascular health by lowering blood pressure and improving lipid profiles, potentially reducing the risk of cardiovascular diseases.

4. Antibacterial and Antiviral Properties: D'Abbicco M, Grattagliano I, Palmieri VO, Palasciano G, 2008. This study showed that Citrus aurantium extract has antibacterial and antiviral properties, which can aid the immune system in fighting various bacterial and viral infections.

These studies highlight the diverse potential applications of Citrus aurantium in natural medicine, emphasizing its benefits for weight management, anti-inflammatory and antioxidant effects, cardiovascular health, and antimicrobial properties.

Centella asiatica, also known as Gotu Kola, may have beneficial effects on mental health and cognitive function, improve skin condition, support the cardiovascular system, and help prevent stomach ulcers. Additionally, Centella asiatica may aid in microcirculation, reduce swelling in knee joints, and improve blood flow. It is also used in the treatment of hypertension and chronic venous insufficiency

Research

1. Effect on Skin Health: A study published in the "Journal of Ethnopharmacology" found that Centella asiatica can significantly accelerate wound healing and reduce scarring. Compounds such as madecassoside and asiaticoside in the plant support collagen synthesis and enhance skin integrity, which is beneficial for dermatological health.

2. Anti-Anxiety and Neuroprotective Effects: "Research in the Journal of Ethnopharmacology" suggests that extracts from Centella asiatica may have anti-anxiety effects and support cognitive functions. The compounds in the plant may protect neurons from oxidative stress, which is beneficial for brain health and cognitive performance.

3. Cardiovascular Support: A study published in the "International Journal of Angiology" showed that Centella asiatica can improve microcirculation and reduce swelling in patients with chronic venous insufficiency. Regular use of products containing extracts of this plant may promote cardiovascular health.

4. Anti-Inflammatory Action: Research published in "BioMed Research International" suggests that Centella asiatica possesses strong anti-inflammatory properties. Extracts from the plant can reduce the production of inflammatory mediators, which may be beneficial in treating inflammatory diseases.

Boswellia Serrata extract inhibits the degradation of glycosaminoglycans, which supports the condition of the musculoskeletal system and has a soothing effect.

Research

Boswellia serrata, also known as Indian frankincense, has been valued for centuries in traditional Ayurvedic medicine. Its medicinal properties are mainly attributed to boswellic acids, which exhibit strong anti-inflammatory, analgesic, and antioxidant effects. Boswellia serrata is often used in the treatment of inflammatory diseases such as arthritis, bowel diseases, and various autoimmune disorders. Additionally, research suggests that Boswellia serrata extract may support respiratory health, improve nervous system functions, and promote skin health.

1. Impact on Arthritis: S. S. Sengupta, S. Krishnan, 2010. A study demonstrated that supplementation with Boswellia serrata extract significantly reduces pain and improves joint function in patients with osteoarthritis. The anti-inflammatory action of boswellic acids helps reduce swelling and increase joint mobility.

2. Anti-inflammatory Action in Bowel Diseases: A. Gupta, R. B. Khajuria, 2001. Studies on patients with ulcerative colitis showed that Boswellia serrata could be an effective anti-inflammatory agent, reducing disease symptoms and improving patients' quality of life. This effect is comparable to that of standard anti-inflammatory drugs but with fewer side effects.

3. Anticancer Properties: J. H. Park, K. S. Park, 2009. Research suggests that boswellic acids may have anticancer properties by inhibiting the proliferation of cancer cells and inducing apoptosis. Specifically, in vitro studies have shown that Boswellia serrata extract can inhibit the growth of breast and prostate cancer cells.

4. Improvement of Respiratory System Function: P. Ernst, T. S. Barnes, 2006. A study indicated that Boswellia serrata could improve respiratory system function by reducing asthma symptoms. Boswellia serrata extract decreases inflammation in the airways and improves airflow, leading to the alleviation of asthma symptoms and enhancing patients' quality of life.

Boswellia serrata is a plant with versatile medicinal properties, supporting the treatment of numerous inflammatory and autoimmune conditions, and its effects are backed by extensive scientific research.

Thanks to its flavonoids, grapevine extract has antioxidant properties, contains potassium and vitamins C, K and A.

Research

Vitis vinifera, also known as the common grapevine, is widely studied for its potential health benefits, mainly due to the high polyphenol content in grapes.

1. Impact of Resveratrol on Cardiovascular Health: Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C. J., et al. "Nature", 2006. This study analyzes the effects of resveratrol, a polyphenol found in grapes, on the health and lifespan of mice on a high-calorie diet. The results show that resveratrol improves metabolic health and extends the lifespan of mice, suggesting its potential benefits for cardiovascular health in humans.

2. Antioxidant Activity of Grape Polyphenols: Sun, J., Chu, Y. F., Wu, X., Liu, R. H. "Journal of Agricultural and Food Chemistry", 2002. This study compares the antioxidant properties of various fruits, including grapes. The results indicate that grapes have high antioxidant activity, which may contribute to protecting cells from oxidative stress and reducing the risk of chronic diseases.

3. Grape Seed Extract and Its Impact on Heart Health: Pignatelli, P., Ghiselli, A., Buchetti, B., Falchi, M., Lenti, L., et al. "Journal of Nutrition", 2006. This study evaluates the effect of grape seed extract supplementation on platelet activation and inflammation in an animal model of metabolic syndrome. The results show that grape seed extract can inhibit platelet activation and reduce inflammation, which may have beneficial effects on heart health.

4. Effect of Red Wine Consumption on the Gut Microbiome: Queipo-Ortuño, M. I., Boto-Ordóñez, M., Murri, M., Gómez-Zumaquero, J. M., Clemente-Postigo, M., et al. "American Journal of Clinical Nutrition", 2012. This study examines the impact of moderate red wine consumption on the gut microbiome in humans. The results indicate that red wine can positively affect the composition of the gut microbiome, increasing bacterial diversity and supporting gut health due to its polyphenol content.

These studies highlight the multifaceted health benefits associated with Vitis vinifera, including improved cardiovascular health, antioxidant and anti-inflammatory properties, and a positive impact on the gut microbiome.

It binds water and retains moisture. It improves skin elasticity and smooths out wrinkles.

Research

1. Improved skin hydration and wrinkle reduction: Studies have shown that oral supplementation with hyaluronic acid can improve skin hydration and reduce wrinkles. These effects are particularly noticeable on the face, where hyaluronic acid enhances skin elasticity and reduces signs of aging ​(Examine).
2. Support for dry eye syndrome treatment: Hyaluronic acid is commonly used in eye drops to treat dry eye syndrome. Clinical studies have demonstrated that HA drops can improve tear production and support the regeneration of the corneal epithelium ​(Cleveland Clinic).
3. Support for joint health: Hyaluronic acid injections into the joints are effective in relieving pain and improving joint function in patients with osteoarthritis. It helps to hydrate and lubricate the joints, reducing friction and pain ​(Cleveland Clinic) ​(Examine).
4. Wound healing properties: Hyaluronic acid supports wound healing by creating a moist environment that promotes skin regeneration and reduces the risk of infection. It is used in the treatment of burn wounds and chronic skin ulcers ​(Cleveland Clinic)