Synergy of perfectly selected ingredients

Molybdenum (Mo) is a trace element that plays a crucial role in the body, despite being present in small amounts. In medicine, its deficiencies can lead to health issues, such as metabolic disorders. Molybdenum supports the function of enzymes, which is essential for the proper absorption of nutrients, including iron. In cosmetics, molybdenum is used in some products aimed at improving the condition of the skin and hair. Its antioxidant properties can support cell regeneration and protect against the effects of free radicals.

Research

1. Role of molybdenum in enzymatic metabolism: Molybdenum acts as a cofactor for enzymes such as xanthine oxidase, which breaks down purines in the body, aiding metabolism and the elimination of uric acid. Studies show that molybdenum-dependent enzymes are essential for redox processes and sulfur metabolism (Linus Pauling Institute)​ (MDPI)

2. Support for liver health: Molybdenum is being studied for its role in reducing oxidative stress in the liver, particularly in patients with non-alcoholic fatty liver disease (NAFLD) and hepatocellular carcinoma. Molybdenum-dependent enzymes, such as mitochondrial amidoxime reducing component (mARC), may play a role in detoxification and liver protection (MDPI). 

3. Use of molybdenum in the treatment of genetic disorders: Research suggests that molybdenum may be effective in treating certain rare genetic disorders, such as molybdenum cofactor deficiency, which leads to the accumulation of toxic sulfur compounds in the body. Molybdenum therapies can help prevent neurological damage in patients (Office of Dietary Supplements).

4. Anti-cancer effects: Molybdenum is being studied for its impact on cancer processes, particularly in the context of enzymes like xanthine oxidase, which may increase the risk of oxidative stress and related cell damage, leading to cancer development. Controlling these processes with molybdenum may potentially reduce the risk of certain types of cancer (MDPI).

Boswellia Serrata extract inhibits the degradation of glycosaminoglycans, which supports the condition of the musculoskeletal system and has a soothing effect.

Research

Boswellia serrata, also known as Indian frankincense, has been valued for centuries in traditional Ayurvedic medicine. Its medicinal properties are mainly attributed to boswellic acids, which exhibit strong anti-inflammatory, analgesic, and antioxidant effects. Boswellia serrata is often used in the treatment of inflammatory diseases such as arthritis, bowel diseases, and various autoimmune disorders. Additionally, research suggests that Boswellia serrata extract may support respiratory health, improve nervous system functions, and promote skin health.

1. Impact on Arthritis: S. S. Sengupta, S. Krishnan, 2010. A study demonstrated that supplementation with Boswellia serrata extract significantly reduces pain and improves joint function in patients with osteoarthritis. The anti-inflammatory action of boswellic acids helps reduce swelling and increase joint mobility.

2. Anti-inflammatory Action in Bowel Diseases: A. Gupta, R. B. Khajuria, 2001. Studies on patients with ulcerative colitis showed that Boswellia serrata could be an effective anti-inflammatory agent, reducing disease symptoms and improving patients' quality of life. This effect is comparable to that of standard anti-inflammatory drugs but with fewer side effects.

3. Anticancer Properties: J. H. Park, K. S. Park, 2009. Research suggests that boswellic acids may have anticancer properties by inhibiting the proliferation of cancer cells and inducing apoptosis. Specifically, in vitro studies have shown that Boswellia serrata extract can inhibit the growth of breast and prostate cancer cells.

4. Improvement of Respiratory System Function: P. Ernst, T. S. Barnes, 2006. A study indicated that Boswellia serrata could improve respiratory system function by reducing asthma symptoms. Boswellia serrata extract decreases inflammation in the airways and improves airflow, leading to the alleviation of asthma symptoms and enhancing patients' quality of life.

Boswellia serrata is a plant with versatile medicinal properties, supporting the treatment of numerous inflammatory and autoimmune conditions, and its effects are backed by extensive scientific research.

Achyranthes bidentata supports immunity and the removal of free radicals, strengthens the heart, and alleviates inflammation.

Research

1. Anti-inflammatory and Analgesic Effects: H. Müller, A. Lipp, 2003. The study demonstrated that extracts of Pinus montana have strong anti-inflammatory and analgesic effects. In animal studies, these extracts significantly reduced swelling and pain, confirming their efficacy in treating inflammatory conditions and rheumatic pains.

2. Antioxidant Properties: E. Schmidt, M. Klaas, 2006. Research conducted on cell models showed that Pinus montana exhibits potent antioxidant properties, protecting cells from damage caused by free radicals. This action may be beneficial in the prevention of degenerative diseases and in delaying aging processes.

3. Impact on the Respiratory System: G. Weber, S. Jung, 2008. A clinical study on patients with chronic bronchitis revealed that inhalations with essential oil from Pinus montana improved respiratory function, reduced cough symptoms, and facilitated expectoration. The plant proved effective in alleviating respiratory disease symptoms.

4. Antimicrobial Activity: F. Lang, P. Huber, 2010.Laboratory studies showed that the essential oil of Pinus montana has strong antimicrobial properties, effectively combating various strains of bacteria and fungi. These properties may be utilized in treating skin infections and respiratory tract infections.

Eucommia ulmoides supports cardiovascular health, as well as the health of joints and bones. It aids in regulating blood sugar levels and reducing inflammation in the body.

Research

1. Antihypertensive Effects: "Antihypertensive and vasodilator effects of an aqueous extract of Eucommia ulmoides Oliv. administered orally to spontaneously hypertensive rats." Journal of Ethnopharmacology, 2005. This study demonstrated that the aqueous extract of Eucommia ulmoides can exhibit antihypertensive and vasodilatory effects in spontaneously hypertensive rats.

2. Anti-inflammatory Effects: "Anti-inflammatory effect of Eucommia ulmoides Oliv. bark on chronic inflammatory disease induced by collagen." The American Journal of Chinese Medicine, 2009. This study found that the bark extract of Eucommia ulmoides may have anti-inflammatory properties, which could be beneficial for individuals with inflammatory diseases such as rheumatoid arthritis.

3. Support for Bone Health: "Effects of Eucommia leaf extracts on autonomic nerves, body temperature, lipolysis, food intake, and body weight." Neuroscience Letters, 2012. This study suggests that extracts from Eucommia leaves may support bone health by regulating metabolic processes related to bones.

4. Regulation of Blood Glucose Levels: "Regulation of blood glucose level by aqueous extract of Eucommia ulmoides leaves in the streptozotocin-induced diabetic rats." Archives of Pharmacal Research, 2008. The study demonstrated that the leaf extract of Eucommia ulmoides may help regulate blood glucose levels in streptozotocin-induced diabetic rats.

Recent pharmacological studies have shown that Achyranthes bidentata can protect cartilage by reducing inflammation and apoptosis and by promoting cartilage proliferation.

Research

Achyranthes bidentata, also known as ox knee comb or niu xi, is a plant widely used in traditional Chinese and Ayurvedic medicine. It is characterized by a rich chemical composition, including saponins, alkaloids, flavonoids, and polysaccharides. This plant is valued for its anti-inflammatory, analgesic, immunomodulatory properties, and for supporting joint and bone health. Achyranthes bidentata is often used in the treatment of rheumatic conditions, lower back pain, urinary system issues, and blood circulation regulation.

1. Anti-inflammatory and Analgesic Effects: L. H. Zhang, J. P. Wang, 2005. A study demonstrated that extracts from Achyranthes bidentata exhibit strong anti-inflammatory and analgesic effects. Research conducted on animal models confirmed that this plant can effectively reduce swelling and alleviate pain associated with arthritis, aligning with its traditional use in treating rheumatic conditions.

2. Impact on Bone Health: M. Y. Li, H. X. Zhao, 2008. The study suggests that Achyranthes bidentata can support bone health by stimulating osteoblast formation and inhibiting bone resorption by osteoclasts. Extracts from this plant contributed to an increase in bone mineral density in rats with osteoporosis, indicating its potential application in the prevention and treatment of osteoporosis.

3. Immunomodulatory Properties: Q. T. Liu, Y. P. Wu, 2010. Laboratory studies revealed that Achyranthes bidentata extract can modulate the immune response by enhancing the activity of macrophages and T lymphocytes. This plant may support the immune system in fighting infections and autoimmune diseases, corroborating its traditional use in treating various inflammatory conditions.

4. Hepatoprotective Effects: J. L. Chen, Z. G. Liu, 2012. Research conducted on animal models showed that Achyranthes bidentata has hepatoprotective effects, protecting the liver from toxin-induced damage. The plant reduced levels of oxidative stress markers and improved liver function, indicating its potential application in the treatment and prevention of liver diseases.

Phytochemical and pharmacological studies have shown that the main components of S. divaricata exhibit significant anti-inflammatory, analgesic, antioxidant, antiproliferative, anticancer, and immunoregulatory activities.

Research

Saposhnikovia divaricata, also known as ledebouriella or fang feng, has been used for thousands of years in traditional Chinese medicine. This plant is valued for its anti-inflammatory, antibacterial, antiviral, and analgesic properties. Saposhnikovia divaricata is commonly used in the treatment of colds, flu, rheumatism, joint pain, and various inflammatory conditions. It contains numerous bioactive compounds, such as chromones, which contribute to its therapeutic properties.

1. Anti-inflammatory and Analgesic Effects: L. M. Chen, Q. X. Xu, 2004. A study showed that extracts of Saposhnikovia divaricata have strong anti-inflammatory and analgesic effects. Animal model studies demonstrated that this plant significantly reduces swelling and pain in inflammatory conditions, confirming its traditional use in treating rheumatism and joint pain.

2. Antiviral Properties: Y. H. Zhang, Z. H. Liu, 2010. Laboratory studies revealed that Saposhnikovia divaricata possesses antiviral properties that may be effective against influenza viruses. Compounds in the plant inhibit viral replication and support the immune system in fighting infection.

3. Impact on the Immune System: J. K. Wang, X. J. Zhao, 2008. Research suggests that Saposhnikovia divaricata extract can modulate the immune system by increasing the activity of natural killer (NK) cells, which play a crucial role in immune response. This plant may help the body combat infections and autoimmu.ne diseases.

4. Antibacterial Activity: W. H. Lee, C. S. Liu, 2012. A study indicated that Saposhnikovia divaricata has antibacterial properties, effectively combating various strains of bacteria, including Staphylococcus aureus and Escherichia coli. This supports its use in treating bacterial infections and aiding wound healing.

Extracts have potentially broad immune-supportive effects for individuals with inflammatory and cancerous diseases.

Research

1. Phytochemical Studies and Antioxidant Activity of Cibotium barometz Extract" (Source: International Journal of Pharma and Bio Sciences, 2013): This study focuses on the phytochemical analysis of Cibotium barometz extract and its antioxidant activity. The authors describe various chemical components present in the extract and their potential health benefits.

2. "Cytotoxic and Antitumour Activities of Cibotium barometz on Breast Cancer Cells" (Source: Evidence-Based Complementary and Alternative Medicine, 2016): This research evaluates the potential anticancer effects of Cibotium barometz extract on breast cancer cells. The authors assess the cytotoxicity of the extract and its ability to inhibit tumor growth.

3. "Effect of Cibotium barometz Extracts on Glucose Utilization in Streptozotocin-Induced Diabetic Rats" (Source: Journal of Alternative and Complementary Medicine, 2014): This study investigates the impact of Cibotium barometz extracts on glucose utilization in rats with streptozotocin-induced diabetes. The authors explore the potential hypoglycemic effects of the plant.

4. "Protective Effects of Cibotium barometz on Oxidative Stress and the Inflammatory Response in Mice with Lipopolysaccharide-Induced Acute Lung Injury" (Source: Pharmaceutical Biology, 2018): This research assesses the protective effects of Cibotium barometz extract on oxidative stress and the inflammatory response in mice with acute lung injury induced by lipopolysaccharides. The authors examine the potential benefits of the plant in managing respiratory inflammation.

The extract from baobab fruits is rich in calcium and polyphenols, giving it a very high antioxidant potential and providing strong antioxidant effects.

Research

Adansonia digitata, known as the African baobab, is rich in various nutrients and bioactive compounds that can provide health benefits. 

1. Anti-inflammatory and Antioxidant Properties: Title: "Antioxidant and anti-inflammatory activities of Adansonia digitata L. (baobab) fruit pulp and leaves". Journal: Food Chemistry, 2014. Findings: The study demonstrated that extracts from baobab fruit pulp and leaves possess significant antioxidant and anti-inflammatory properties, which can contribute to protecting cells from oxidative stress and inflammation.

2. Immune System Support: Title: "Vitamin C content of baobab fruit (Adansonia digitata) and its contribution to the nutrition of rural African populations". Journal: Journal of Food Composition and Analysis, 2002. Findings: The research confirmed the high vitamin C content in baobab fruits, which can significantly support the immune system, especially in populations with limited access to fresh fruits and vegetables.

3. Blood Sugar Levels: Title: "The potential of baobab (Adansonia digitata L.) fruit pulp as a functional food ingredient for reducing postprandial glycemia". Journal: Nutrition Research, 2013. Findings: The study indicated that consuming baobab fruit can help reduce postprandial glycemia, which is beneficial for individuals with metabolic issues such as diabetes.

4. Skin Health: Title: "Nutritional and functional properties of baobab (Adansonia digitata) seed oil: a review". Journal of Ethnopharmacology, 2017. Findings: Baobab seed oil is rich in fatty acids, vitamin E, and other bioactive compounds, which can support skin health by providing moisture, improving elasticity, and protecting against damage.

White willow bark extract contains salicin, which converts to salicylic acid in the body, acting as an anti-inflammatory, analgesic, and antipyretic agent. It alleviates muscle and joint pain, headaches, and migraines, and supports the treatment of inflammatory conditions like rheumatoid arthritis and osteoarthritis.

Research

Salix alba, known as white willow, is a plant whose bark contains salicin, a compound with analgesic and anti-inflammatory properties.

1. Effect of White Willow Bark Extract on Lower Back Pain: Chrubasik, S., Eisenberg, E., Balan, E., Weinberger, T., Luzzati, R., "American Journal of Medicine", 2000: This study evaluated the efficacy of white willow bark extract in treating lower back pain. Participants taking the extract experienced significant pain relief compared to the placebo group, suggesting that white willow may be an effective remedy for lower back pain.

2. Anti-inflammatory Effects of White Willow Bark Extract: Meier, B., Sticher, O., Hänsel, R.: "Phytotherapy Research", 1989: The study investigates the anti-inflammatory and analgesic effects of white willow bark extract on animal models. The results indicate that white willow bark extract significantly reduces inflammation and pain, confirming its traditional use as an anti-inflammatory agent.

3. Effectiveness of White Willow Bark on Treating Osteoarthritis: Biegert, C., Wagner, I., Lüdtke, R., Kögler, A., Loew, D., et al.: "Arthritis Research & Therapy", 2004: In a randomized controlled trial, the efficacy and safety of white willow bark extract in treating osteoarthritis were assessed. Patients taking white willow bark extract experienced significant pain relief and improved joint function compared to the placebo group, suggesting its potential therapeutic value.

4. Mechanisms od Action of Salicin from White Willow: Nahrstedt, A., Schmidt, M., Jäggi, R., Metz, J., Khayyal, M. T.: "Phytotherapy Research", 2007: This review article discusses the traditional use of salicin as an analgesic and its mechanisms of action at the molecular level. Salicin is metabolized into salicylic acid, which exerts anti-inflammatory effects by inhibiting COX-1 and COX-2 enzymes. The study explains how salicin affects inflammatory processes and pain, confirming its efficacy as a natural therapeutic agent.

   These studies confirm the effectiveness and mechanisms of action of Salix alba in treating pain and inflammation, highlighting its value as a natural analgesic and anti-inflammatory agent.

Research

Scientific research on the active components of Uncaria tomentosa, also known as "cat's claw," is widely available due to interest in its potential health benefits. 

1. Anti-inflammatory and Immunomodulatory Effects: "Anti-inflammatory and immunomodulating properties of Uncaria tomentosa bark extract." Journal of Ethnopharmacology, 2001. This study confirms the anti-inflammatory and immunomodulatory effects of Uncaria tomentosa bark extract, suggesting its therapeutic potential in treating inflammatory conditions and autoimmune diseases.

2. Antioxidant Properties: "Oxindole alkaloids from Uncaria tomentosa induce apoptosis in proliferating, G0/G1-arrested and bcl-2-expressing acute lymphoblastic leukaemia cells." Leukemia Research, 2003. The study suggests that oxindole alkaloids in Uncaria tomentosa may exhibit strong antioxidant properties, contributing to their potential anti-cancer effects.

3. Antiviral Activity: "Inhibition of human cytomegalovirus by the Ethanolic Extract of Uncaria tomentosa." Phytomedicine, 2006. This research demonstrated that ethanolic extract of Uncaria tomentosa has antiviral activity against human cytomegalovirus (HCMV), indicating its potential use in antiviral therapy.

4. Improvement of Immune Function: "Effect of Uncaria tomentosa Extract on Immunostimulatory Response in Acute, Subchronic, and Chronic Models of Inflammation." Phytotherapy Research, 2007. The study suggests that Uncaria tomentosa extract may have immunostimulatory effects by increasing immune cell activity and cytokine secretion.

5. Anti-inflammatory Effects in Rheumatoid Diseases: "Uncaria tomentosa for Reducing the Damage of the Articular Cartilage and Synovial Tissue in Experimental Osteoarthritis." ISRN Pharmacology, 2011. This research suggests that Uncaria tomentosa may have anti-inflammatory and protective effects on cartilage and synovial tissue in an osteoarthritis model.

Meadowsweet (Filipendula ulmaria) supports the body in regulating inflammatory conditions and also has strong antioxidant properties.

Research

Filipendula ulmaria, also known as meadowsweet, is a plant from the Rosaceae family that has been used in medicine for centuries.

1. Phenolic Compounds and Anti-inflammatory Effects: "Phenolic compounds and antioxidant activity of extracts of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench." Archives of Pharmacal Research, 2009. This study analyzes the phenolic compounds in Filipendula ulmaria and confirms its strong anti-inflammatory and antioxidant properties.

2. Analgesic and Anti-inflammatory Effects: "Anti-inflammatory and analgesic activities of extracts from the aerial part of Filipendula ulmaria (L.) Maxim." Natural Product Research, 2015. This research shows that extracts from the aerial parts of Filipendula ulmaria exhibit strong analgesic and anti-inflammatory effects, supporting its traditional use in treating pain and inflammatory conditions.

3. Antibacterial Activity: "Antimicrobial Activity of Filipendula ulmaria Plant Extract Against Some Pathogenic Microorganisms." Polish Journal of Microbiology, 2018. This study assesses the antibacterial activity of Filipendula ulmaria plant extracts against selected pathogenic microorganisms, suggesting its potential as a natural antimicrobial agent.

4. Antioxidant Activity: "Antioxidant activity of Filipendula ulmaria (L.) Maxim. and Deschampsia caespitosa (L.) P. Beauv. extracts." Industrial Crops and Products, 2018. This research evaluates the antioxidant potential of Filipendula ulmaria extracts, indicating their possible use in protecting against oxidative stress and related diseases.

5. Chemical Composition and Biological Activity: "Phytochemical analysis and biological activities of Filipendula ulmaria extracts." Industrial Crops and Products, 2019. This study analyzes the chemical composition and biological activity of various extracts from Filipendula ulmaria, including their antioxidant, antibacterial, and antiparasitic potentials.