Synergy of perfectly selected ingredients

Ashwagandha is known as a calming adaptogen. Therefore, it may help with fatigue and insomnia. Additionally, it reduces perimenopausal symptoms, improves sperm vitality and motility, and is a powerful antioxidant.

Research

1. Impact on Cognitive Functions: A study focused on adults experiencing perceived stress showed that ashwagandha supplementation may improve cognitive abilities, lower cortisol levels, enhance mood, and reduce anxiety, stress, and food cravings (SpringerLink).

2. Versatile Health Benefits: Ashwagandha is being researched for its neuroprotective, sedative, and adaptogenic properties. Furthermore, studies suggest its potential anti-inflammatory, antibacterial, cardioprotective, antidiabetic effects, as well as its influence on reproductive health and thyroid hormones (MDPI).

3. Hematological and Biochemical Benefits: A systematic review of studies involving healthy adults found that ashwagandha supplementation may improve various hematological and biochemical markers, hormone levels, and antioxidant response, indicating its support for overall health (SpringerLink).

4. Anti-stress Properties and Nervous System Support: Research indicates that ashwagandha may be helpful in managing stress, improving cognitive functions, and enhancing immunity. Its active components, withanolides, exhibit anti-inflammatory effects, which may contribute to its beneficial impact on neurological health and the ability to cope with stress (MDPI).

Purple passionflower helps to relax, calm down, regenerate and fall asleep, recommended for overworked and tired people.

Research

Passiflora incarnata is an herb known for its calming properties and ability to alleviate symptoms of stress and insomnia. Traditionally, this plant has been used as a natural remedy to support healthy sleep and overall mental well-being.

1. Sedative and Anxiolytic Properties: Passiflora incarnata is known for its calming effects, which may help in alleviating symptoms of anxiety and stress. It is commonly used as a natural aid to support healthy sleep and general mental well-being.

2. Impact on Sleep Quality: DH Dhawan, Anil Kumar, D Goel, V Gupta, 2001. Studies suggest that Passiflora incarnata may improve sleep quality by inducing a sense of relaxation and restful sleep, making it helpful for individuals dealing with insomnia.

3. Analgesic Properties: Jairo Kenupp Bastos, Elita Scio, Hugo Silva Santos, Geraldo Reis, Luiz Rocha, 2000. Some research indicates the potential of Passiflora incarnata as a pain-relieving agent, particularly in alleviating headaches and tension-related discomfort.

4. Antioxidant Properties: Tijen Akdogan, Ismail Kilic, Hasan Olmez, Mustafa Akyol, Yusuf Celik, Atiye Sogut, 2006. Extracts from Passiflora incarnata contain antioxidant compounds that may help protect cells from oxidative stress and free radical damage.

Cherry fruit extract contains vitamin C and melatonin, which helps regulate the natural cycle of body activity and improve sleep efficiency.

Research

Prunus cerasus, commonly known as sour cherry, is a fruit that has garnered scientific interest due to its potential health benefits.

Scientific research:

1. Effect of Cherry Juice on Inflammation and Oxidative Stress in Athletes: Kuehl, K. S., Perrier, E. T., Elliot, D. L., Chesnutt, J. C. "British Journal of Sports Medicine," 2010. This study evaluates the impact of cherry juice on muscle soreness and recovery processes following intense physical exercise. The results suggest that consuming cherry juice before and after exercise may reduce muscle soreness and accelerate recovery due to its anti-inflammatory and antioxidant properties.

2. Antioxidant and Anti-inflammatory Properties of Cherry Extract: Wang, H., Nair, M. G., Strasburg, G. M., Booren, A. M., Gray, J. I., DeWitt, D. L. "Journal of Natural Products," 1999. This study investigates the anti-inflammatory and antioxidant effects of anthocyanins isolated from cherries in a mouse model of colitis. The findings indicate that cherry anthocyanins may reduce inflammation and oxidative stress, suggesting their potential use in treating inflammatory bowel diseases.

3. Impact of Cherry Juice Consumption on Sleep: Howatson, G., Bell, P. G., Tallent, J., Middleton, B., McHugh, M. P., Ellis, J. "European Journal of Nutrition," 2012. This study assesses the effect of cherry juice consumption on melatonin levels and sleep quality. Participants who consumed cherry juice had higher melatonin levels and reported better sleep quality compared to the control group, suggesting that cherry juice may be a natural sleep aid.

4. Protective Potential of Cherry Juice in Cardiovascular Diseases: Keane, K. M., George, T. W., Constantinou, C. L., Brown, M. A., Clifford, T., Howatson, G. "Journal of the American Heart Association," 2016. This study examines the effect of cherry juice consumption on blood pressure in older adults. The results show that cherry juice consumption may lower blood pressure, potentially contributing to reduced risk of cardiovascular diseases due to its polyphenol content with anti-inflammatory and antioxidant properties.

These studies highlight the potential health benefits associated with consuming Prunus cerasus, including reduced inflammation, improved sleep quality, antioxidant effects, and support for cardiovascular health.

Supplementation with Ziziphus jujuba, also known as Chinese date, offers many potential health benefits. Extracts from this plant help calm the body, which may aid in stress reduction and improve sleep quality. Ziziphus jujuba is rich in antioxidants, which help combat free radicals, and it also exhibits anti-inflammatory properties. Supplementation may support the digestive system by improving digestion and alleviating symptoms related to digestive disorders.

Research

1. Therapeutic effects of Ziziphus jujuba in traditional and modern medicine: A study published in "Therapeutic Effects of Ziziphus jujuba Mill. Fruit in Traditional and Modern Medicine" indicates that jujube is used to treat various diseases, including asthma, bronchitis, constipation, and cardiovascular diseases, due to its anti-inflammatory and antioxidant properties​ (Welcome to Bentham Science Publisher)​.

2. Impact of Ziziphus jujuba consumption on metabolic factors: A study published in "Clinical Nutrition Open Science" revealed that regular consumption of jujube can improve lipid profiles by lowering LDL, triglycerides, and total cholesterol levels, which may contribute to weight management and BMI reduction​ (Welcome to Bentham Science Publisher)​.

3. Health benefits and bioactive compounds of Ziziphus jujuba: An article in "Recent advances on bioactive compounds, health benefits, and potential applications of Ziziphus jujuba" highlights that jujube is rich in bioactive compounds such as polyphenols, flavonoids, polysaccharides, and saponins, which possess strong antioxidant, antibacterial, and anti-inflammatory properties​ (Welcome to Bentham Science Publisher)​.

4. Effect of Ziziphus jujuba on mental health: A study published in "Evidence-Based Complementary and Alternative Medicine" indicates that jujube has neuroprotective effects, protecting nerve cells from neurotoxic stress and stimulating neuronal differentiation, which may support brain health​ (Welcome to Bentham Science Publisher)​.

Adaptogen. Golden root i ncreases adaptability to environmental conditions; increases the organism's tolerance to stress factors.

Research

1. Improvement of Cognitive Abilities and Reduction of Fatigue: Spasov AA, Wikman GK, Mandrikov VB, Mironova IA, Neumoin VV, 2004. A study conducted on young doctors working night shifts showed that supplementation with Rhodiola rosea improves cognitive abilities and reduces fatigue, indicating the potential use of this plant in stressful conditions.

2. Increased Cognitive Function and Reduced Fatigue: Shevtsov VA, Zholus BI, Shervarly VI, Vol'skij VB, Korovin YP, Khristich MP, Roslyakova NA, Wikman G, 2003. This study suggests that Rhodiola rosea enhances cognitive function and reduces feelings of fatigue in healthy individuals, indicating a positive effect of this plant on overall mental performance.

3. Support in Depression Treatment: Darbinyan V, Aslanyan G, Amroyan E, Gabrielyan E, Malmstrom C, Panossian A, 2007. The study found that supplementation with Rhodiola rosea may aid in the treatment of depression by improving mood and reducing depressive symptoms. The results suggest the potential use of Rhodiola rosea in depression therapy.

4. Effectiveness Against Mental and Physical Fatigue: Olsson EM, von Schéele B, Panossian AG, 2009. In a study involving medical students, Rhodiola rosea was found to effectively reduce both mental and physical fatigue. Participants who took the herb reported better physical and mental condition compared to the control group.

Supplementation with Griffonia simplicifolia, a plant rich in 5-HTP (5-hydroxytryptophan), can provide benefits for mental health. 5-HTP is a precursor to serotonin, a neurotransmitter that affects mood and emotions. Supplementing with 5-HTP may help reduce symptoms of depression, anxiety, and improve sleep quality. It also acts as a weight management aid by potentially reducing appetite and cravings.

Research

1. Antioxidant and metabolic properties of Griffonia simplicifolia seed extracts: A study published in Antioxidants analyzed the metabolomic profile and antioxidant, antiproliferative, and antibacterial properties of Griffonia simplicifolia seed extracts. The results showed that aqueous and hydroalcoholic extracts exhibited the highest antioxidant activity. Moreover, these extracts demonstrated antiproliferative effects against HeLa, HepG2, and MCF-7 cancer cell lines, as well as antibiotic action against Staphylococcus aureus​ (MDPI)​.

2. Biological activity and sustainable use of Griffonia simplicifolia: A study published in Challenges evaluated the beneficial properties of Griffonia simplicifolia, such as antioxidant effects and protection against oxidative stress in astrocytes and neurons. The study also found antimalarial activity of aqueous extracts against Plasmodium falciparum and nephroprotective effects in rats with kidney damage induced by gentamicin and cisplatin​ (MDPI)​.

3. Effects of 5-HTP from Griffonia simplicifolia on sexual behavior in rats: A study published in the Journal of Sexual Medicine investigated the effects of 5-hydroxytryptophan (5-HTP) derived from Griffonia simplicifolia seeds on sexual behavior in rats. Results showed that administering 5-HTP at a dose of 100 mg/kg/day for nine days led to significant reductions in body weight and food intake, as well as increased serotonin levels in the brain​ (Examine.com)​.

4. Therapeutic potential of Griffonia simplicifolia in clinical studies: Several clinical studies have explored the therapeutic potential of Griffonia simplicifolia extracts. One study by Rondanelli et al. found that 5-HTP supplementation for one month increased satiety and reduced BMI in overweight women. Another study showed that a combination of Griffonia simplicifolia extract and magnesium could help manage motion sickness symptoms in children​ (MDPI)​​ (Examine.com)​.

Eschscholtzia californica, commonly known as California poppy, is a plant with numerous potential health benefits. Primarily used to alleviate symptoms of anxiety and improve sleep quality, its calming properties may contribute to reducing stress and tension. California poppy extract also aids individuals dealing with pain, making it useful in treating headaches and muscle pain. Additionally, this plant is rich in alkaloids, which may support the nervous system.

Research

1. Effects on sleep and anxiety: A clinical study showed that a combination of California poppy extract, hawthorn, and magnesium effectively reduced symptoms of mild to moderate anxiety. The study found this treatment to be safe and more effective than a placebo​ (ClinicalTrials.gov).

2. Pain management: Research has demonstrated that California poppy may be effective in treating pain, including pain associated with chronic conditions and insomnia caused by pain. Its analgesic properties are attributed to alkaloids such as protopine and californidine​ (The Botanical Institute).

3. Anxiolytic and calming effects: Eschscholtzia californica is used as a sedative, often employed to reduce stress and anxiety, as well as to promote sleep. Animal studies have confirmed its strong anxiolytic and sleep-promoting properties​ (The Botanical Institute).

4. Safety of use: California poppy is considered safe when used in recommended doses, although caution is advised during pregnancy and breastfeeding. No significant drug interactions or adverse health effects have been reported with proper use​ (The Botanical Institute).

Melatonin is a hormone produced by the pineal gland that plays a key role in regulating the circadian rhythm of sleep and wakefulness. In medicine, it is used to treat sleep disorders such as insomnia and in the therapy of individuals with jet lag. Melatonin also has antioxidant properties, making it a valuable ingredient in cosmetics. In skincare, melatonin protects the skin from the harmful effects of UV radiation and neutralizes free radicals, supporting regenerative processes. It is particularly recommended for the care of tired, acne-prone skin and in night skincare products.

Research

1. Wpływ melatoniny na sen i bezsenność: Melatonina jest powszechnie stosowana w leczeniu bezsenności oraz poprawie jakości snu. Badania kliniczne potwierdzają, że melatonina może skrócić czas zasypiania, zwłaszcza u osób cierpiących na zaburzenia snu związane z pracą zmianową lub jet lag. W metaanalizach zauważono, że regularna suplementacja melatoniną poprawia długość i jakość snu​ (BioMed Central)​ (BioMed Central)

2. Działanie przeciwzapalne i antyoksydacyjne: Melatonina wykazuje silne właściwości antyoksydacyjne, które mogą chronić komórki przed stresem oksydacyjnym. Badania wskazują, że może ona zmniejszać markery stanu zapalnego, wspomagając zdrowie serca i układu krążenia. Jest to szczególnie ważne w kontekście ochrony przed przewlekłymi chorobami zapalnymi​ (BioMed Central).

3. Wsparcie zdrowia psychicznego: Melatonina ma również potencjalne zastosowanie w leczeniu depresji sezonowej (SAD) oraz jako środek wspomagający stabilizację nastroju. Badania wykazały, że regulacja cyklu snu poprzez melatoninę może poprawiać samopoczucie u pacjentów cierpiących na depresję ​(BioMed Central).

4. Wspomaganie zdrowia kości: Badania wskazują, że melatonina może wspomagać regenerację kości, zwłaszcza u osób starszych. Działa poprzez regulację metabolizmu kostnego oraz wspieranie równowagi hormonalnej, co zmniejsza ryzyko osteoporozy​ ​ (BioMed Central).

Vitamin A is an extremely important vitamin that plays a crucial role in the functioning of our body. It has a significant role in the process of vision, affects growth, and regulates the growth of epithelial tissue and other cells in the body.

Research

Vitamin A is crucial for many biological processes in the body, including eye health, immune system function, and cell development.

1. Impact of Vitamin A on Eye Health: Sommer, A. "Annual Review of Nutrition," 1982.  This study discusses the role of Vitamin A in retinal function and its importance in preventing night blindness. Retinal, a derivative of Vitamin A, is a key component of rhodopsin, a pigment in the retina's photoreceptors essential for vision in low light conditions.

2. Vitamin A and the Immune System: Ross, A. C. "The American Journal of Clinical Nutrition," 2010. This study examines how Vitamin A affects the immune response, including antibody production and activation of immune cells. Vitamin A is a crucial factor in regulating the immune response, especially concerning respiratory infections and diarrhea in children.

3. Role of Vitamin A in Fetal Development: Clagett-Dame, M., DeLuca, H. F. "Annual Review of Nutrition," 2002. This study focuses on the role of retinoic acid, the active form of Vitamin A, in cell differentiation and organogenesis during embryonic development. Retinoic acid affects the expression of genes crucial for the proper development of body structures, such as limbs, the heart, and the nervous system.

4. Vitamin A Supplementation and Child Health in Developing Countries: Imdad, A., Herzer, K., Mayo-Wilson, E., Yakoob, M. Y., Bhutta, Z. A. "Cochrane Database of Systematic Reviews," 2010. This systematic review evaluates the impact of Vitamin A supplementation on child mortality in developing countries. The results indicate that Vitamin A supplementation significantly reduces child mortality due to infections like measles and diarrhea, highlighting the importance of supplementation strategies in health programs.

These studies underscore the multifaceted role of Vitamin A in human health, from vision to immune functions and fetal development.